After the war, the Hotel Alfa Luxembourg remained a place of cultural and local political life.
In 1973, the interior of the Hotel Alfa underwent a major redesign under the direction of architect Pierre Bohler.
In 1997, the Hotel Alfa was entirely renovated, and an annex was built. In the following two decades, the Accor Group took over the management of the hotel under the brand Grand Mercure. In 2017, the then hotel’s tenant ceased operations.